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Symbol
Name
ID

Srf
serum response factor
MGI:106658

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Pulmonary lymphangiomyomatosis	Abnormality of the lymphatic system	Lymphadenopathy	Recurrent respiratory infections
Disease(s) Associated with SRF
lymphangioleiomyomatosis

Mouse Phenotypes		athymia	decreased thymocyte number	decreased B-1 B cell number	absent marginal zone B cells	decreased B cell number	decreased CD4-positive, alpha-beta T cell number	decreased CD8-positive, alpha-beta T cell number	decreased T cell number	abnormal mature B cell morphology
Availability	Mouse Genotype	athymia	decreased thymocyte number	decreased B-1 B cell number	absent marginal zone B cells	decreased B cell number	decreased CD4-positive, alpha-beta T cell number	decreased CD8-positive, alpha-beta T cell number	decreased T cell number	abnormal mature B cell morphology
	Srf^tm1Rmn/Srf^tm1Rmn H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)
	Srf^tm2Nor/Srf^tm2Nor Tg(Cd4-cre)1Cwi/? (conditional)
	Srf^tm2Nor/Srf^tm2Nor Cd19^tm1(cre)Cgn/Cd19⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23